{"id":1274,"date":"2025-03-13T15:00:00","date_gmt":"2025-03-13T15:00:00","guid":{"rendered":"https:\/\/retina-eye.co.uk\/?p=1274"},"modified":"2026-10-22T15:28:00","modified_gmt":"2026-10-22T15:28:00","slug":"personalised-medical-treatment-for-diabetic-macular-oedema-dmo-the-role-of-imaging-biomarkers","status":"publish","type":"post","link":"https:\/\/www.retina-eye.co.uk\/zh\/post\/personalised-medical-treatment-for-diabetic-macular-oedema-dmo-the-role-of-imaging-biomarkers\/","title":{"rendered":"\u4e2a\u6027\u5316\u7684\u533b\u7597\u6cbb\u7597\u7684\u7cd6\u5c3f\u75c5\u89c6\u7f51\u819c\u9ec4\u6591\u6c34\u80bf(DMO)\u7684\u4f5c\u7528\u50cf\u751f\u7269\u6807\u5fd7"},"content":{"rendered":"<p class=\"wp-block-paragraph\" id=\"viewer-hgt4l410\">Ms\u6c99\u9f99\u5174\u5177\u6709\u6df1\u611f\u5174\u8da3\u7684\u4e2a\u6027\u5316\u6cbb\u7597\u548c\u7279\u522b\u8ba4\u4e3a\uff0c\u5728\u5e76\u5229\u7528\u9002\u5f53\u7684\u50cf\u751f\u7269\u6807\u8bb0\uff0c\u4ee5\u786e\u5b9a\u5904\u7406\u7684\u9884\u6d4b\u3001\u53cd\u5e94\u548c\u4f5c\u4e3a\u6307\u5bfc\u9009\u62e9\u5408\u9002\u7684\u7b2c\u4e00\u7ebf\u6cbb\u7597\u5bf9\u60a3\u6709\u7cd6\u5c3f\u75c5\u89c6\u7f51\u819c\u9ec4\u6591\u6c34\u80bf.<\/p>\r\n\r\n\r\n\r\n<p class=\"wp-block-paragraph\" id=\"viewer-vghb3427\">\u5979\u5750\u5728\u751f\u7269\u6807\u5fd7\u6307\u5bfc\u59d4\u5458\u4f1a\u4e3a\u827e\u4f2f\u7ef4\u2013\u533b\u7597\u624b\u81c2\u7684\u5236\u836f\u516c\u53f8\uff0c\u8be5\u516c\u53f8\u751f\u4ea7\u7684ozurdex\u690d\u5165\u7269\u3002 \u4e00\u8d77\u4e0e\u5176\u4ed6\u59d4\u5458\u4f1a\uff0c\u4ed6\u4eec\u7684\u5efa\u8bae\u548c\u7ed9\u8f93\u5165\u5230\u4ea7\u751f\u4e34\u5e8a\u624b\u518c\u5bf9\u533b\u7597\u4fdd\u5065\u4e13\u4e1a\u4eba\u5458\u4f5c\u4e3a\u6307\u5bfc\u4f7f\u7528\u7684\u751f\u7269\u6807\u5fd7\u7ba1\u7406\u7684DMO\u3002<\/p>\r\n\r\n\r\n\r\n<h2 id=\"viewer-ea2jc443\" class=\"wp-block-heading\">\u4ec0\u4e48\u662f\u4e2a\u6027\u5316\u7684\u533b\u7597\u6cbb\u7597\uff1f<\/h2>\r\n\r\n\r\n\r\n<p class=\"wp-block-paragraph\" id=\"viewer-t4pa3445\">\u4e2a\u6027\u5316\u7684\u533b\u836f\uff0c\u8fd9\u662f\u5426\u4e5f\u79f0\u4e3a\u7cbe\u51c6\u533b\u7597\uff0c\u662findividualising\u533b\u7597\u51b3\u7b56\u548c\u5e72\u9884\u63aa\u65bd\u9002\u5408\u4e8e\u7279\u5b9a\u4e2a\u4eba\u6216\u5b9a\u6cbb\u7597\u8ba1\u5212\u7684\u4e2a\u4eba\u3002\u00a0<\/p>\r\n\r\n\r\n\r\n<p class=\"wp-block-paragraph\" id=\"viewer-m7teh619\">\u4e2a\u6027\u5316\u6216\u7cbe\u5bc6\u533b\u7597\u6cbb\u7597\uff0c\u6211\u4eec\u5e0c\u671b\u80fd\u591f\u9009\u62e9\u4e00\u79cd\u6cbb\u7597\u6700\u9002\u5408\u60a3\u8005\u3001\u5c11\u526f\u4f5c\u7528\u53ef\u80fd\u6700\u597d\u7684\u53ef\u80fd\u7ed3\u679c\u3002 \u8fd9\u5c06\u662f\u57fa\u4e8e\u4e2a\u4eba\u7684\u72ec\u7279\u60c5\u51b5\uff0c\u5305\u62ec\u4e34\u5e8a\u3001\u533b\u7597\u548c\u793e\u4f1a\u3002<\/p>\r\n\r\n\r\n\r\n<p class=\"wp-block-paragraph\" id=\"viewer-3nfqo649\">\u6bcf\u4e2a\u4eba\u90fd\u662f\u552f\u4e00\u4e0d\u540c\u7684\u9057\u4f20\u7f16\uff0c\u8fd9\u53ef\u80fd\u5f71\u54cd\u5b83\u4eec\u5982\u4f55\u4f53\u73b0\u67d0\u4e9b\u75be\u75c5\uff0c\u5e94\u5bf9\u67d0\u4e9b\u75be\u75c5\uff0c\u75be\u75c5\u7684\u4e25\u91cd\u7a0b\u5ea6\u548c\u5bf9\u6cbb\u7597\u7684\u53cd\u5e94\u3002 \u4f8b\u5982\uff0c\u75c5\u4eba\u7684\u9057\u4f20\u503e\u5411\u7684\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\u7684\uff0c\u4f8b\u5982\u6b66\u56682\u6216\u9648\u822a\u5cf0\u57fa\u56e0\u53ef\u80fd\u8f83\u65e9\u51fa\u73b0\u7684\u9ad8\u7ea7\u9636\u6bb5\u7684\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\u548c\u53ef\u80fd\u9700\u8981\u66f4\u5bc6\u5207\u7684\u76d1\u6d4b\u3002<\/p>\r\n\r\n\r\n\r\n<p class=\"wp-block-paragraph\" id=\"viewer-0whna592\">\u5f53\u4e00\u4e2a\u4eba\u88ab\u8bca\u65ad\u60a3\u6709\u75be\u75c5\uff0c\u51b3\u5b9a\u5728\u6cbb\u7597\u4f60\u63d0\u4f9b\uff0c\u901a\u5e38\u5c06\u57fa\u4e8e\u7ed3\u679c\u7684\u5e73\u5747\u4ece\u8f83\u5927\u7684\u4eba\u53e3\u4ece\u4e34\u5e8a\u7814\u7a76\uff0c\u4f46\u662f\uff0c\u60a3\u8005\u53ef\u4ee5\u4ee5\u4e0d\u540c\u7684\u65b9\u5f0f\u54cd\u5e94\u5728\u4e2a\u4eba\u5c42\u9762\uff0c\u8fd9\u5c31\u662f\u6211\u4e86\u89e3\u7684\u75c5\u4eba\u6863\u6848\uff0c\u4f7f\u3001\u4e34\u5e8a\u6982\u51b5\uff0c\u836f\u7269\u7684\u526f\u4f5c\u7528\u548c\u6f5c\u5728\u7684\u7ed3\u679c\u662f\u91cd\u8981\u7684\uff0c\u5728\u786e\u5b9a\u6700\u597d\u7684\u6cbb\u7597\uff0c\u7279\u522b\u662f\u4e2a\u4eba\u3002\u8fdb\u4e00\u6b65\u7684\u4e2a\u6027\u5316\u6cbb\u7597\u4e5f\u662f\u5173\u4e8e\u6539\u5584\u8bca\u65ad\u548c\u9884\u6d4b\u7684\u53ef\u80fd\u6027\uff0c\u6709\u4eba\u53d1\u5c55\u7684\u6761\u4ef6\uff0c \u548c\u505c\u6b62\u7684\u4e00\u4e2a\u6761\u4ef6\u6076\u5316\uff0c\u6b63\u5982\u5728\u8f83\u65e9\u7684\u4f8b\u5b50AMD\u3002<\/p>\r\n\r\n\r\n\r\n<h2 id=\"viewer-z9nns453\" class=\"wp-block-heading\">\u4ec0\u4e48\u662fDMO?<\/h2>\r\n\r\n\r\n\r\n<p class=\"wp-block-paragraph\" id=\"viewer-ugnr5455\">\u7cd6\u5c3f\u75c5\u773c\u6db5\u76d6\u4e86\u82e5\u5e72\u6761\u4ef6\uff0c\u53ef\u4ee5\u5f71\u54cd\u7684\u4eba\u7684\u773c\u775b\u6709\u7cd6\u5c3f\u75c5\uff0c\u5305\u62ec\u7cd6\u5c3f\u75c5\u89c6\u7f51\u819c\u75c5\u3001\u7cd6\u5c3f\u75c5\u89c6\u7f51\u819c\u9ec4\u6591\u6c34\u80bf(DMO)\u3001\u548c\u767d\u5185\u969c\u3002 \u6700\u5e38\u89c1\u7684\u662f\u7cd6\u5c3f\u75c5\u89c6\u7f51\u819c\u75c5\u53d8\u3001\u5176\u53d1\u751f\u65f6\u7684\u9ad8\u8840\u7cd6\u6c34\u5e73\u9020\u6210\u635f\u5bb3\u7684\u5fae\u5c0f\u8840\u7ba1\u5728\u89c6\u7f51\u819c\u3002\u00a0<\/p>\r\n\r\n\r\n\r\n<p class=\"wp-block-paragraph\" id=\"viewer-mebh2566\">DMO is a complex, multifactorial disease which may result in visual loss. In cases of high sugar or hyperglycaemia can result in the breakdown of the blood\u2013retinal barrier (BRB), promoting oxidative stress and the release of inflammatory\u00a0 which leads to increased retinal vascular permeability. As a result, there is accumulation of intra- and subretinal fluid (IRF\/SRF) fluid in the macular and visual impairment.<\/p>\r\n\r\n\r\n\r\n<h2 id=\"viewer-pj0th459\" class=\"wp-block-heading\">\u4ec0\u4e48\u662f\u751f\u7269\u6807\u5fd7?<\/h2>\r\n\r\n\r\n\r\n<p class=\"wp-block-paragraph\" id=\"viewer-w7rf6461\">Biomarkers are traits that doctors measure in your\u00a0blood, tissues, and clinical imaging. There are several categories of biomarkers, examples include:<\/p>\r\n\r\n\r\n\r\n<ul class=\"wp-block-list\">\r\n<li>\u7ec4\u7ec7\uff0c\u4f8b\u5982\uff0cBRCA1\/2<\/li>\r\n\r\n\r\n\r\n<li>Radiographic, e.g., radiographic evidence of tumour shrinkage<\/li>\r\n\r\n\r\n\r\n<li>\u751f\u7406\uff0c\u4f8b\u5982\uff0c\u8840\u538b\u548chba1c<\/li>\r\n<\/ul>\r\n\r\n\r\n\r\n<p class=\"wp-block-paragraph\" id=\"viewer-2c7ye717\">\u751f\u7269\u6807\u5fd7\u53ef\u7528\u4e8e\u9884\u6d4b\u548c\u76d1\u6d4b\u5bf9\u6cbb\u7597\u7684\u53cd\u5e94\u3002\u00a0<\/p>\r\n\r\n\r\n\r\n<h2 id=\"viewer-k7ot2475\" class=\"wp-block-heading\">\u5982\u4f55\u751f\u7269\u6807\u5fd7\u5e2e\u52a9\u5728\u7ba1\u7406DMO?<\/h2>\r\n\r\n\r\n\r\n<p class=\"wp-block-paragraph\" id=\"viewer-8yehy477\">Physiological biomarkers such as hypertension, hypercholesterolaemia, and blood sugar tests are important associated factors to optimise diabetic retinopathy control. Numerous studies over the decade have found the association of better sugar and blood pressure control in maintaining diabetic retinopathy status.\u00a0<\/p>\r\n\r\n\r\n\r\n<p class=\"wp-block-paragraph\" id=\"viewer-h6bc1778\">\u9ad8\u8fbe30\uff05\u7684\u60a3\u8005\u7684\u6700\u4f73\u63a7\u5236\u7cd6\u53ef\u4ee5\u663e\u793a\u6539\u8fdb\u5b83\u4eec\u7684\u7cd6\u5c3f\u75c5\u89c6\u7f51\u819c\u9ec4\u6591\u6c34\u80bf. \u4e0e\u63a8\u8fdb\u5728\u6210\u50cf\u548c\u591a\u7684\u6210\u50cf\u65b9\u5f0f\uff0c\u6709\u4e00\u79cd\u589e\u52a0\u7684\u5174\u8da3\u770b\u770b\u6444\u50cf\u751f\u7269\u6807\u8bb0\u5982\u679c\u67d0\u4e9b\u8ff9\u8c61\u53ef\u4ee5\u9884\u6d4b\u6216\u9884\u8a00\u75be\u75c5\u7684\u7ed3\u679c\uff0c\u6216\u5bf9\u6cbb\u7597\u7684\u53cd\u5e94\u3002<\/p>\r\n\r\n\r\n\r\n<p class=\"wp-block-paragraph\" id=\"viewer-xm1uc808\">\u4f8b\u5982\u4f7f\u7528\u67d0\u4e9b\u8c03\u67e5\u7ed3\u679c\u5728\u626b\u63cf\uff0c\u6211\u4eec\u53ef\u4ee5\u786e\u5b9a\u5982\u4f55\u4e25\u91cd\u6216\u6162\u6027DMO\u53ef\u80fd\u5e76\u4e14\u5982\u679c\u6cbb\u7597\u53ef\u4ee5\u6539\u5584\u7684\u613f\u666f\u548c\u6211\u4eec\u7136\u540e\u53ef\u4ee5\u57fa\u4e8e\u8c03\u67e5\u7ed3\u679c\uff0c\u5efa\u8bae\u75c5\u4eba\u7684\u9884\u671f\u76f8\u5e94\u3002\u00a0<\/p>\r\n\r\n\r\n\r\n<h2 id=\"viewer-6guay484\" class=\"wp-block-heading\">\u4f8b\u7684\u6210\u50cf\u7684\u751f\u7269\u6807\u5fd7?<\/h2>\r\n\r\n\r\n\r\n<p class=\"wp-block-paragraph\" id=\"viewer-9sz7v486\">\u8fd9\u7bc7\u6587\u7ae0\u4e0d\u662f\u7a77\u5c3d\u6240\u6709\u7684\u751f\u7269\u6807\u5fd7\u6211\u4eec\u5ba1\u67e5\u4e86\u4e34\u5e8a\u7684\u57fa\u7840\u3002 \u4f5c\u4e3a\u4f8b\u5b50\uff0c\u901a\u5e38\u6240\u77e5\u7684\u751f\u7269\u6807\u5fd7\u5305\u62ec\u5982\u4e0b\uff1a<\/p>\r\n\r\n\r\n\r\n<h3 id=\"viewer-2yg4y488\" class=\"wp-block-heading\">Intraretina\u56ca\u80bf<\/h3>\r\n\r\n\r\n\r\n<p class=\"wp-block-paragraph\" id=\"viewer-x95eg490\">\u5728DMO\uff0c\u7ea2\u65b0\u6708\u4f1a\u7684\u5f62\u5f0f\u8f85\u4ee5\u79ef\u6db2\u5728\u89c6\u7f51\u819c\u4e0a\u770b\u5230OCT\u6210\u50cf\u3002 \u8fd9\u4e9b\u56ca\u6837\u7a7a\u95f4\u7684\u7279\u70b9\u662f\u5b83\u4eec\u7684\u5177\u4f53\u4f4d\u7f6e\u5728\u89c6\u7f51\u819c\u5c42\uff0c\u4ee5\u53ca\u4ed6\u4eec\u7684\u53cd\u5c04\u7387\u548c\u89c4\u6a21\u3002 \u4f8b\u5982\uff0c\u5927\u56ca\u6837\u7684\u7a7a\u95f4\u6700\u5c11\u7684\u5269\u4f59\u7684\u89c6\u7f51\u819c\u7ec4\u7ec7\u901a\u5e38\u4e0e\u6162\u6027.\u00a0<\/p>\r\n\r\n\r\n\r\n<h3 id=\"viewer-r3cu9492\" class=\"wp-block-heading\">Hyper-\u53cd\u5c04\u7684\u75c5\u7076<\/h3>\r\n\r\n\r\n\r\n<p class=\"wp-block-paragraph\" id=\"viewer-4mc84494\">Hyper-\u53cd\u5c04\u7684\u91cd\u70b9\u662f\u5c0f\uff0c\u70b9\u5f62\uff0chyperreflective\u75c5\u53ef\u89c1OCT\u56fe\u50cf\u7684\u89c6\u7f51\u819c\u3002 \u5728DMO\uff0c\u8fd9\u4e9b\u88ab\u8ba4\u4e3a\u4ee3\u8868\u8102\u5145\u6ee1\u5de8\u566c\u7ec6\u80de\u6216\u80f6\u8d28\u7ec6\u80de\u8fd9\u53ef\u80fd\u8868\u660e\u708e\u75c7\u3002<\/p>\r\n\r\n\r\n\r\n<figure class=\"wp-block-image size-full\"><img fetchpriority=\"high\" decoding=\"async\" class=\"alignnone wp-image-1276 size-full\" src=\"https:\/\/www.retina-eye.co.uk\/wp-content\/uploads\/2026\/03\/fa5924_9c3821efdb1e43a580b27c0f3ecf356cmv2.avif\" alt=\"OCT scan showing intra-retina cysts and hyper-reflective foci as imaging biomarkers for DMO\" width=\"875\" height=\"239\" srcset=\"https:\/\/www.retina-eye.co.uk\/wp-content\/uploads\/2026\/03\/fa5924_9c3821efdb1e43a580b27c0f3ecf356cmv2.avif 875w, https:\/\/www.retina-eye.co.uk\/wp-content\/uploads\/2026\/03\/fa5924_9c3821efdb1e43a580b27c0f3ecf356cmv2-300x82.avif 300w, https:\/\/www.retina-eye.co.uk\/wp-content\/uploads\/2026\/03\/fa5924_9c3821efdb1e43a580b27c0f3ecf356cmv2-768x210.avif 768w\" sizes=\"(max-width: 875px) 100vw, 875px\" \/><\/figure>\r\n\r\n\r\n\r\n<h2 id=\"viewer-qfddn1102\" class=\"wp-block-heading\">\u4ec0\u4e48\u6837\u7684\u6cbb\u7597\u662f\u7528\u4e8eDMO?<\/h2>\r\n\r\n\r\n\r\n<h3 id=\"viewer-sttqa1104\" class=\"wp-block-heading\">\u6fc0\u5149\u6cbb\u7597(\u6fc0\u5149\u51dd\u56fa)<\/h3>\r\n\r\n\r\n\r\n<p class=\"wp-block-paragraph\" id=\"viewer-1c8kb1106\">One of the most common treatments for diabetic eye disease is laser photocoagulation. This procedure uses a laser to target and seal off leaking blood vessels in the retina, which helps to prevent further damage and stabilises vision.\u00a0<\/p>\r\n\r\n\r\n\r\n<p class=\"wp-block-paragraph\" id=\"viewer-z39sr1108\">\u6fc0\u5149\u662f\u4f7f\u7528\u4f5c\u4e3a\u4e00\u79cd\u6cbb\u7597\u6b96\u6027\u7cd6\u5c3f\u75c5\u89c6\u7f51\u819c\u75c5\u548c\u7cd6\u5c3f\u75c5\u89c6\u7f51\u819c\u9ec4\u6591\u6c34\u80bf. \u8be5\u7a0b\u5e8f\u901a\u5e38\u662f\u5728\u4e00\u4e2a\u95e8\u8bca\u75c5\u4eba\u8bbe\u5b9a\u5e76\u5177\u6709\u6700\u5c0f\u7684\u526f\u4f5c\u7528\u3002<\/p>\r\n\r\n\r\n\r\n<h2 id=\"viewer-f5cqg1110\" class=\"wp-block-heading\">\u6297\u8840\u6ce8\u5c04\u7684\u57fa\u77f3DMO\u6cbb\u7597<\/h2>\r\n\r\n\r\n\r\n<p class=\"wp-block-paragraph\" 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